Biomimetic Materials And Design: Biointerfacial Strategies, Tissue Engineering And Targeted Drug Delivery

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Angela Dillow, Anthony Lowman
CRC Press, Aug 28, 2002 - Medical - 696 pages
Detailing techniques in wound healing and reconstruction, this reference describes the mechanisms and architecture of biological systems to formulate and design natural and synthetic compounds, degradable and non-degradable scaffolds, and targeted drug delivery devices. It offers strategies to control adhesive interactions, elicit specific cellular responses, and improve the biocompatibility, performance, and durability of prosthetic materials. Covering advances in the field, the book discusses the effect of topographical features on cell behaviors such as orientation, adhesion, migration, proliferation, and differentation.
 

Contents

Use of Supported Thin Films of Peptide Amphiphiles as Model Systems of the Extracellular Matrix to Study the Effects of StructureFunction Phenom...
1
Engineering of IntegrinSpecific Biomimetic Surfaces to Control Cell Adhesion and Function
29
Mimetic PeptideModified Materials for Control of Cell Differentiation
55
Effects of Substratum Topography on Cell Behavior
91
Cytomimetic Biomaterials Fabrication Characterization and Applications
139
Micro and Nanoscale Organizations of Proteins Modulate CellExtracellular Matrix Interactions Lessons for the Design of Biomaterials
159
Cell AdhesionDependent Signaling Pathways on Biomaterials Surfaces
187
Biomaterials Synthetic and Engineering Strategies
251
Biomimetic Strategies and Applications in the Nervous System
375
Tissue Engineering Strategies for Axonal Regeneration Following Spinal Cord Injury
417
Micropatterning Biomimetic Materials for Bioadhesion and Drug Delivery
443
Bioinspired Engineering of Intelligent Drug Delivery Systems and ProteinPolymer Conjugates
471
Implantable Drug Delivery Devices Design of a Biomimetic Interfacial Drug Delivery System
507
Pharmacologically Active Biomaterials
533
Biomimetic Lung Surfactant Replacements
565
Peptide Nucleic Acid PNA Conjugates in Biotechnology
635

Scaffolds for Directing Cellular Responses and Tissue Formation
283
Chitosan as a Molecular Scaffold for Biomimetic Design of Glycopolymer Biomaterials
311
CellInternalizable Ligand Microinterfaces on Biomaterials Design of Regulatory Determinants of Cell Migration
335

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About the author (2002)

Angela Dillow (3M Health Care, St Paul, Minnesota, USA) (Edited by) , Anthony Lowman (Drexel University, Philadelphia, Pennsylvania, USA) (Edited by)

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